osteogenesis imperfecta

Definition of Osteogenesis Imperfecta in English :

1. osteogenesis imperfecta

autosomal dominant disorder of connective tissue characterized by brittle bones that fracture easily

WordNet Lexical Database for English. Princeton University. 2010.

Osteogenesis Imperfecta

noun

a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities

. Also called: brittle bone syndrome

a rare hereditary disorder of connective tissue, characterized by thin, brittle bones and progressive deafness

n.

A genetic disease marked by abnormal fragility and plasticity of bone, with recurring fractures resulting from minimal trauma.